The 2026 Mercedes-Benz E-Class delivers an EPA-certified 21–28 MPG combined across 14 configurations. Estimated annual fuel costs range from $2,700 to $3,600.
Factual efficiency differences across gasoline, hybrid, plug-in hybrid, and electric variants
Annual Fuel Cost: $2,700–$3,600 (saves vs gas).
Gasoline Combined: 24 MPG • Annual Cost: $3,150.
Laboratory certification test values across engine, transmission, and drivetrain permutations
| Configuration / Model | Powertrain | Drivetrain | Transmission | City | Highway | Combined | EV Range | Annual Fuel Cost | CO2 (g/mi) |
|---|---|---|---|---|---|---|---|---|---|
| E350 Premium | 2L Hybrid | Rear-Wheel Drive | Automatic 9-spd | 25 MPG | 33 MPG | 28 MPG | — | $2,700 | — |
| CLE300 4matic (Coupe) Premium | 2L Hybrid | All-Wheel Drive | Automatic 9-spd | 24 MPG | 33 MPG | 27 MPG | — | $2,800 | — |
| E350 4matic Premium | 2L Hybrid | All-Wheel Drive | Automatic 9-spd | 24 MPG | 33 MPG | 27 MPG | — | $2,800 | — |
| CLE300 4matic (Convertible) Premium | 2L Hybrid | All-Wheel Drive | Automatic 9-spd | 23 MPG | 32 MPG | 26 MPG | — | $2,900 | — |
| CLE450 4matic (Convertible) Premium | 3L Hybrid | All-Wheel Drive | Automatic 9-spd | 23 MPG | 32 MPG | 26 MPG | — | $2,900 | — |
| CLE450 4matic (Coupe) Premium | 3L Hybrid | All-Wheel Drive | Automatic 9-spd | 23 MPG | 33 MPG | 26 MPG | — | $2,900 | — |
| E450 4matic Premium | 3L Hybrid | All-Wheel Drive | Automatic 9-spd | 22 MPG | 31 MPG | 25 MPG | — | $3,050 | — |
| E450 4matic All-Terrain (wagon) Premium | 3L Hybrid | All-Wheel Drive | Automatic 9-spd | 22 MPG | 31 MPG | 25 MPG | — | $3,050 | — |
| AMG E53 Hybrid 4matic Plus Premium and Electricity | 3L Plug-in Hybrid | All-Wheel Drive | Automatic 9-spd | 55 MPGe (22 MPG) | 68 MPGe (27 MPG) | 60 MPGe (24 MPG) | 44 mi | $3,150 | — |
| GLE350 Premium | 2L Hybrid | Rear-Wheel Drive | Automatic 9-spd | 21 MPG | 28 MPG | 23 MPG | — | $3,300 | — |
| AMG E53 Hybrid 4matic Plus (station wagon) Premium and Electricity | 3L Plug-in Hybrid | All-Wheel Drive | Automatic 9-spd | 52 MPGe (21 MPG) | 64 MPGe (25 MPG) | 56 MPGe (22 MPG) | 41 mi | $3,450 | — |
| GLE350 4matic Premium | 2L Hybrid | All-Wheel Drive | Automatic 9-spd | 19 MPG | 26 MPG | 22 MPG | — | $3,450 | — |
| GLE450 4matic Premium | 3L Hybrid | All-Wheel Drive | Automatic 9-spd | 19 MPG | 25 MPG | 21 MPG | — | $3,600 | — |
| GLE450 4matic (coupe) Premium | 3L Hybrid | All-Wheel Drive | Automatic 9-spd | 19 MPG | 25 MPG | 21 MPG | — | $3,600 | — |
Standardized annual energy consumption and operating cost metrics based on 15,000 annual miles
Based on $3.50 per gallon regular gasoline
Estimated annual energy units needed for 15,000 miles
Compared to the average new vehicle over 5 years
Cross-reference safety ratings, owner defect complaints, and recall campaigns
Vehicle summary, specifications, and primary KPI metrics.
NHTSA 5-Star NCAP crash tests, rollover risk, and active driver assistance.
NHTSA consumer defect complaint filings by affected component.
Official safety recall notices, defects, and free repair instructions.
Direct, deterministic answers synthesized from verified United States government databases for the 2026 Mercedes-Benz E-Class
The 2026 Mercedes-Benz E-Class achieves an EPA-certified rating of 21 to 28 MPG combined across 14 certified configuration(s).
City ratings range from 19 to 28 MPG, and highway ratings range from 21 to 33 MPG.
The 2026 Mercedes-Benz E-Class plug-in hybrid (PHEV) delivers up to 0 miles of all-electric driving range before transitioning to hybrid gasoline operation.
In electric mode, efficiency is rated at 24 MPGe, switching to 0 MPG combined on gasoline.
Using AutoUtility's standardized operating cost model, estimated annual fueling and energy costs range between $2,700 and $3,600 for the 2026 Mercedes-Benz E-Class.
Calculated under AutoUtility's standardized methodology (15,000 miles per year, 55% city / 45% highway driving, $3.50/gallon regular gasoline, $0.16/kWh electricity) using official EPA dynamometer consumption ratings.
Fuel economy ratings, electric range figures, and energy cost estimates on this page are retrieved directly from the United States Environmental Protection Agency (EPA) and U.S. Department of Energy (FuelEconomy.gov) certified vehicle database under 40 CFR Part 600.
Local Production Store Compiled: August 2026 • Deterministic Audited Dataset • Zero Dynamic External API Runtime Latency.