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Combined MPG
22 MPG
55% city / 45% highway weighted
City Driving Rating
19 MPG
Stop-and-go urban cycle
Highway Driving Rating
28 MPG
Sustained open-highway test
Annual Fuel Cost
$2,800
EPA estimate @ 15,000 miles/yr
Laboratory Fuel Economy Certification

Executive Efficiency Findings

The 2021 Honda Odyssey delivers an EPA-certified 22 MPG combined across 1 configuration. Estimated annual fuel costs range from $2,800 to $2,800.

EPA Testing Standards: Ratings derived from official dynamometer laboratory tests under 40 CFR Part 600. Real-world fuel economy varies based on driving style, ambient temperature, cargo payload, and terrain.
Certified Powertrain Attributes
  • • Certified Configurations: 1 trim and powertrain permutation(s).
  • • Combined Rating Range: 22 MPG.
  • • Annual Energy Cost: $2,800 (15k mi/yr).
Certified Ratings Matrix

Official EPA Fuel Economy Ratings by Configuration (1)

Laboratory certification test values across engine, transmission, and drivetrain permutations

Configuration / Model Powertrain Drivetrain Transmission City Highway Combined Annual Fuel Cost CO2 (g/mi)
Odyssey Regular 3.5L 6-Cyl Gas Front-Wheel Drive Automatic (S10) 19 MPG 28 MPG 22 MPG $2,800 —
Operating Cost Economics

Standardized Energy Cost & Consumption Benchmarks

Standardized annual energy consumption and operating cost metrics based on 15,000 annual miles

ENERGY UNIT 25 MI

Fuel Cost per 25 Miles

$3.98–$3.98

Based on $3.50 per gallon regular gasoline

ANNUAL TOTAL 15K MI

Annual Fuel Consumption

682–682 Gal

Estimated annual energy units needed for 15,000 miles

5-YEAR VALUE SAVINGS

5-Year Fuel Cost vs Avg Vehicle

EPA Benchmark

Compared to the average new vehicle over 5 years

Related Workstations

Related Official Reports for 2021 Honda Odyssey

Cross-reference safety ratings, owner defect complaints, and recall campaigns

← 2021 Honda Odyssey Overview

Vehicle summary, specifications, and primary KPI metrics.

2021 Honda Odyssey Safety Ratings →

NHTSA 5-Star NCAP crash tests, rollover risk, and active driver assistance.

2021 Honda Odyssey Owner Complaints (136) →

NHTSA consumer defect complaint filings by affected component.

2021 Honda Odyssey Safety Recalls (8) →

Official safety recall notices, defects, and free repair instructions.
Search Intelligence

Quick Answers: EPA Fuel Economy, Electric Range & Energy Costs for the 2021 Honda Odyssey

Direct, deterministic answers synthesized from verified United States government databases for the 2021 Honda Odyssey

What gas mileage (MPG) does the 2021 Honda Odyssey get?

The 2021 Honda Odyssey achieves an EPA-certified rating of 22 MPG combined across 1 certified configuration(s).

City ratings range from 19 to 19 MPG, and highway ratings range from 28 to 28 MPG.

Source: EPA FuelEconomy.gov (40 CFR Part 600)

What is the estimated annual fuel or energy cost for the 2021 Honda Odyssey?

Using AutoUtility's standardized operating cost model, estimated annual fueling and energy costs range between $2,800 for the 2021 Honda Odyssey.

Calculated under AutoUtility's standardized methodology (15,000 miles per year, 55% city / 45% highway driving, $3.50/gallon regular gasoline, $0.16/kWh electricity) using official EPA dynamometer consumption ratings.

Source: AutoUtility Operating Cost Model (EPA-Certified Baseline)
Official US Government Data Provenance

Fuel economy ratings, electric range figures, and energy cost estimates on this page are retrieved directly from the United States Environmental Protection Agency (EPA) and U.S. Department of Energy (FuelEconomy.gov) certified vehicle database under 40 CFR Part 600.

Local Production Store Compiled: August 2026 • Deterministic Audited Dataset • Zero Dynamic External API Runtime Latency.